345 Park Avenue South Office Space

Your next lab space doesn’t have to feel like a sterile box in some forgettable office tower. At 345 Park Avenue South office space, you get something different – a building in Midtown South that actually understands what you need to get work done.

A Building With Real History That Works for Modern Science

Here’s the deal: this building started as an armory in 1912, designed by William H. Whittal. You probably don’t care about old architecture, but you should care about what happened next. Deerfield bought it in 2021 and gutted the entire thing, spending serious money to turn it into CURE., a proper life sciences and healthcare facility. They kept the cool historic bones but ripped out everything that would slow you down. Now you get high ceilings and character, plus all the modern systems your equipment actually needs. No more choosing between a building that looks good and one that works well.

Spaces That Fit How You Work

When you walk through 345 Park Avenue South office space, you’ll see 300,000 square feet spread across 12 floors, with floorplates from 25,750 to 27,400 square feet. Every floor comes pre-wired for whatever you’re building – wet labs, dry labs, device testing areas, or just regular office space. You don’t have to beg your landlord to install special electrical or figure out how to retrofit outdated systems. The cabling is already there for digital health applications, and you can configure spaces however your work demands. Whether you need a quiet prototype studio or a full lab setup, the building adapts to you instead of forcing you to work around its limitations.

Amenities That Actually Enhance Your Work Experience

Your building amenities extend far beyond basic necessities, creating an environment where productivity and collaboration flourish naturally. These carefully curated spaces help you attract top talent while keeping your current team engaged and motivated.

• Rooftop Terrace: Host client meetings or team events with stunning Manhattan skyline views as your backdrop. Your guests will remember presentations delivered in this unique setting.
• Exclusive Wine Cellar: Celebrate project milestones or close important deals in a sophisticated space designed for memorable moments. Your team deserves recognition in style.
• State-of-the-Art Conference Center: Present research findings or pitch investors in professionally equipped spaces with the latest technology. Your presentations will shine with proper audiovisual support.
• Fitness Center: Maintain your health and energy levels without leaving the building during busy workdays. Your wellness routine stays consistent even during crunch periods.
• Lounge Club and Kitchen: Build relationships with colleagues over coffee or grab a quick meal between experiments. Your informal conversations often lead to breakthrough ideas.

Location That Makes Sense

You work at 345 Park Avenue South office space, which means you’re in Silicon Alley, right in the middle of where tech and life sciences companies actually want to be. Multiple subway lines stop nearby in the heart of Gramercy Park, so your commute doesn’t eat your entire day. Madison Square Park is right there when you need a break from staring at screens. Moreover, the Flatiron District surrounds you with decent restaurants and coffee shops that don’t charge airport prices. You can walk to meetings with other companies, investors, or collaborators without planning your entire day around travel time.

Companies You’d Want as Neighbors

Right now, 345 Park Avenue South office space houses Deerfield, ProTara Therapeutics, Test Now and Go, Bank of America Financial Center, Helaina, and Upland Restaurant on the ground floor. You get move-in-ready spaces from 10,900 to 27,000 square feet, so whether you’re a 20-person startup or a growing company that needs room to expand, you can find something that fits. Your neighbors understand deadlines, compliance requirements, and why you sometimes need to work weird hours.